Gabapentin for Anxiety in Dogs

Key Takeaway: Gabapentin (Neurontin®) is a prescription drug that has been used by humans for decades to treat seizures, pain, and anxiety. In dogs it is used to treat anxiety. Some side effects can include drowsiness, fatigue, and weight gain with long-term use. Gabepentin is fairly inexpensive.


Canine anxiety has many causes – fireworks or other loud noises, separation anxiety, PTSD from a previous abusive owner, or illness can all cause dogs to have bad cases of nervous excitedness. If you’ve taken your pet to the vet for these problems, your vet may have prescribed a drug called gabapentin or Neurontin. 

This article covers some critical information on gabapentin use in canine anxiety. Read on to learn what you need to know to take care of your dog!


Gabapentin (brand name Neurontin) has been used for decades in humans for seizure control, pain control, and mood stability, including treatment for anxiety. Gabapentin has also been studied for use in dogs and cats. 1

The research so far shows that gabapentin is safe and effective for canine anxiety when used at the right doses.

Remember that gabapentin is a prescription only drug and should only be used under the supervision of a veterinarian.


According to the Merck Veterinary Manual, side effects of gabapentin in dogs tend to be mild and limited. 1   They are as follows:

  • Drowsiness
  • Fatigue
  • Weight gain with long-term use


An effective dose for gabapentin for anxious dogs as given in one study is 25-30 milligrams per kilogram, or around 11-13 milligrams per pound. It’s used directly before a trigger that causes anxiety (going to the vet, fireworks, etc).

 See our chart below to see where your dog would fall in this dosing!


This table shows weight-based dosing for canine anxiety in dogs. The 100mg and 300mg capsule columns show you how many of each strength you'd need to make up the right dose. 

100mg and 300mg capsules are the most common and lowest cost dose forms at most pharmacies. 3

Weight (kg) Weight (lbs) Dose in mg # 100mg capsules # 300mg capsules
2.2 5 55 N/A N/A
4.5 10 112 1 N/A
6.8 15 112 1 N/A
9.1 20 227 2 N/A
11.3 25 339 N/A 1
13.6 30 340 N/A 1
15.8 35 474 1 1
18.1 40 500 2 1
20.4 45 600 N/A 2
23.7 50 600 N/A 2
24.9 55 700 1 2
27.2 60 700 1 2
29.5 65 800 2 2
31.8 70 800 2 2
34.0 75 900 N/A 3
36.3 80 1000 1 3


Gabapentin is inexpensive, costing around $0.10-$0.13 per capsule. 3


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I'm Chris; I started Relievet to help my dog Biscuit deal with her mobility issues naturally. Relievet is a family-owned business composed of a team of passionate pet parents that includes a Doctor of Pharmacy, a dog trainer, a writer, a psychologist, and more. We make natural products that help dogs maintain balance and deal with the issues they face, and we do our best to educate people on natural pet health. Beyond that, we are conducting research in hopes of improving the lives of many more animals.

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