When we see our dog in pain, it's natural for us to want to take immediate action to help them feel better.
Before you grab your dog aspirin from the medicine cabinet, STOP.
Dogs should never be given human medication except under the direction of a veterinarian. The results can be hazardous and even fatal in some cases.
Table Of Contents
What is Aspirin
Dosage Of Asprin
Side Effects Of Asprin
Cost Of Asprin
How does Aspirin interact with other drugs?
Are there any Alternatives to Aspirin?
What is Aspirin?
Aspirin is a widely used over-the-counter non-steroidal anti-inflammatory drug (NSAID).
As Aspirin is so readily available, people often ask the question: can I give my dog Aspirin?
In some cases, vet's may prescribe Aspirin for dogs suffering from a variety of conditions, including osteoarthritis and musculoskeletal inflammation.
Aspirin has anti-inflammatory properties, which can help reduce the pain and swelling from many ailments.

Dosage of Aspirin
The Food and Drug Administration (FDA) hasn't approved Aspirin for use; therefore, there is no definitive research to determine the proper dosage of Aspirin for dogs.
Overdoses of Aspirin can be fatal, so you should always talk to your vet and confirm the dosage before giving it to your dog.
As a general guideline, you can use the following table to determine the recommended dosage.
Dog’s Weight
| Aspirin Dosage
|
---|---|
5 (or less) lbs. | 25-50 mg. |
5-10 lbs. | 50-100 mg. |
10-20 lbs. | 100-200 mg. |
20-40 lbs. | 200-400 mg. |
40-60 lbs. | 300-600 mg. |
60-80 lbs. | 400-800 mg. |
80 (or more) lbs. | 500-1000 mg. |
Side effects of Aspirin
If your dog is displaying one or more of the following symptoms, immediately stop giving your dog aspirin and contact your vet.
- Vomiting
- Diarrhea or black, tarry stool
- Mucosal erosion
- Ulceration
- Change in appetite
The following symptoms could indicate an Aspirin overdose:
- Liver or kidney disease
- Acid-based abnormalities
- Hemorrhage
- Seizure
- Coma
- Death
Aspirin can have more severe side effects than other NSAIDs, so you must watch your dog closely while they are taking this medication.
Cost of Aspirin
You can buy and administer Aspirin to your dog in different forms, such as tablets, chewable, or liquid drops. The price will differ depending on the brand, dosage, and quantity per bottle.
The drug store or vet office you buy it from can also impact the difference in price.
How does Aspirin interact with other drugs?
As many drugs can have harmful interactions when taken with Aspirin, you may want to seek safer, natural alternatives. Here are few drugs which can have potentially harmful interactions with Aspirin:
Drug | Drug |
---|---|
ACE inhibitors | Alendronate |
Aminoglycosides | Anticoagulants |
Blood glucose-lowering agents | Calcium Channel Blockers
|
Carbonic Anhydrase inhibitors | Captopril |
Corticosteroids | Digoxin |
Enalapril | Furosemide |
Gentamycin | Glucosamine |
Heparin | Hyaluronidase |
Insulin | Methotrexate |
Oral Anticoagulants | Other NSAIDs |
Pentosane Polysulfate Sodium | Phenobarbital |
Probenecid | Propranolol |
Spironolactone | SSRI antidepressants |
Sulfinpyrazone | Tetracycline |
Tiludronte | Urinary Acidifying |
Urinary Alkalinizing | Valproate products |
Vitamin E |
If you are still planning to give your dog aspirin, it’s important to tell your vet about any medications (including supplements or vitamins) that your dog is taking to avoid potentially harmful side effects.

Are there any Alternatives to Aspirin?
Many studies have explored CBD as an alternative to pharmaceuticals for pain in dogs, including pain from arthritis, mobility issues, and inflammation, but though research is positive, there is not enough evidence to say it is a viable alternative.
One of the various side effects of Aspirin is seizures, unlike CBD, which has the potential to reduce the frequency of or even stop seizures.
Some dogs may experience side effects, including dry mouth, lowered blood pressure, or drowsiness, but these are all reversible by merely reducing the dosage or stopping.
In conclusion, early research shows that CBD has the potential to help with pain, but you should always go to the vet for a diagnosis if you think your dog is in pain, as they are qualified to diagnose the issue.
References:
https://www.petpoisonhelpline.com
https://www.ncbi.nlm.nih.gov
https://www.ncbi.nlm.nih.gov
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